FROM:     NRG Oncology Operations

DATE:      July 26, 2019

NRG-GY014 suspended to endometrial patients, ovarian suspension imminent


Protocol Title: “A Phase II Study of Tazemetostat (EPZ-6438) (IND #138671) in Recurrent or Persistent Endometrioid or Clear Cell Carcinoma of the Ovary, and Recurrent or Persistent Endometrioid Endometrial Adenocarcinoma”

Study Chair:  Ramez Eskander, M.D., (858) 822-6199; email:


This study has reached the maximum allowable accrual for the endometrial patients (stage 1 accrual is complete). Accrual to the endometrial patients has been suspended today: July 26, 2019.The study may reopen to this population in 6 to 9 months after an efficacy and toxicity evaluation. The study remains open to ovarian patients but population is nearing the maximum allowable accrual and may suspend at any time. Please alert any ovarian patients you may be consenting that the trial is very close to meeting accrual goal and they may not be able to be entered.

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