July 15, 2019
NRG Oncology Broadcast archives are accessible from our website at any time. Please bookmark  this link  for your convenience.

Pre-registration is now Closed! Please register onsite at the meeting.

Registration and meeting information is available on the  NRG Oncology website.


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Pre-registration is now Closed! Please register onsite at the meeting.

Registration and meeting information is available on the NRG Oncology website.

 

Get the Meeting App – EVENTSXD

Download EVENTSXD to your electronic device to quickly access agendas, meeting room information, and more! Create an account and select the NRG Oncology Semiannual Meeting. Access the Agenda and create your own personal agenda by tapping the green star in order to “favorite” specific sessions.

CCD 800-line Coverage during the Meeting
Information regarding the availability of the NRG Oncology-Pittsburgh Center Clinical Coordinating Department (CCD) during the NRG Oncology meeting is posted to the NRG Oncology website and the CTSU website.

 

Meeting Highlights

  • Patient-Reported Outcomes: Upping the game for PRO methods and design in clinical trials. NRG Oncology will be holding a workshop at the NRG Semiannual Meeting related to improving statistical methods to meet study goals, analyzing longitudinal PRO data, as well as a panel discussion with NCORP PIs. This session will be held on Thursday, July 18, 2019 from 1-5pm and will be open to all attendees. The agenda can be found here.
  • Summer Symposium: Thursday, July 18 - 8am-3pm  Read more
  • Scientific Session: Friday, July 19 - 8-10am Read more
  • Health Disparities Workshop Special Session: Sexual and Gender Minority Related Activities at the NIH - Friday, July 19 - 10-11:30am  Read more
  • Social Media Workshop: Friday, July 19 - 11:30am -12:30pm  Read more

CTN/CRA Educational Programs

Slide sets for the CTN/CRA Workshop and Educational Lunch Session and handouts for the CTN/CRA Workshop Roundtable Educational Session on Thursday, July 18, 2019, are posted to Nurses and CRA/Education and Training on the NRG Oncology website (password is required). If you plan to attend these sessions, please download the slides prior to the meeting and bring them with you. No handouts will be provided at the meeting. Also, please check the NRG Oncology website frequently prior to the meeting, as additional presentations may be added.

 

SAVE THE DATE: Information Session for NRG-BN006
NRG Oncology will be holding an information session for NRG-BN006: "A Phase II/III Randomized, Open-Label Study of Toca 511, A Retroviral Replicating Vector, Combined with Toca FC with Temozolomide and Radiation Followed by Adjuvant Temozolomide and Toca FC Compared to Temozolomide and Radiation Followed by Adjuvant Temozolomide in Patients with Newly Diagnosed Glioblastoma," on Friday, July 19, 2019 from 10:30-11am ET in Franklin room #13 on the 4th floor of the Marriott during the NRG Oncology Semiannual Meeting in Philadelphia, which will be open to all attendees. Please contact Erin Moye at moyee@nrgoncology.org for any questions.

SAVE THE DATE: Kick-Off Session for NRG-GU007

NRG Oncology will be holding a kick-off session for NRG-GU007: "Randomized Phase II Trial of Niraparib with Standard Combination Radiotherapy and Androgen Deprivation Therapy (ADT) in High Risk Prostate Cancer (with Initial Phase I)," on Friday, July 19, 2019 from 11am-12pm ET in Franklin room #13 on the 4th floor of the Marriott during the NRG Oncology Semiannual Meeting in Philadelphia, which will be open to all attendees. Please contact Erin Moye at moyee@nrgoncology.org for any questions.

 

SAVE THE DATE: Kick-Off Session for NRG-LU003

NRG Oncology will be holding a kick-off session at the NRG Oncology Semiannual Meeting for NRG-LU003: “A Biomarker-Driven Protocol for Previously Treated ALK-Positive Non-Squamous NSCLC Patients: The NCI-NRG ALK Protocol.” The session will be held on Saturday, July 20, 2019 from 10:30-11:30am ET in room 105AB on the first level of the Convention Center, which will be open to all attendees. Please contact Erica Field at fielde@nrgoncology.org for any questions.

 

SAVE THE DATE: Kick-Off Session for NRG-LU005
NRG Oncology will be holding an kick-off session for NRG-LU005: Limited Stage Small Cell Lung Cancer (LS-SCLC): A Phase II/III Randomized Study of Chemoradiation Versus Chemoradiation Plus Atezolizumab, on Friday, July 19, 2019 from 3-4pm ET in Franklin room #13 on the 4th floor of the Marriott during the NRG Oncology Semiannual Meeting in Philadelphia, which will be open to all attendees.  Please contact Erin Moye at moyee@nrgoncology.org for any questions.

 

SAVE THE DATE: Information Session for SWOG/NRG S1806

NRG Oncology will be holding an information session for SWOG/NRG S1806: “Phase III Trial of Concurrent Chemoradiation with or without Atezolizumab for Localized Muscle Invasive Bladder Cancer: SWOG/NRG Intergroup Trial (S1806),” on Friday, July 19, 2019 from 12:00-1:00 PM ET in Franklin room #7 on the 4th floor of the Marriottduring the NRG Oncology Semiannual Meeting in Philadelphia, which will be open to all attendees. Tickets for those who registered for a box lunch will be included in your meeting registration package.  Please contact Treena Davis-Trotman at Davis-TrotmanT@NRGOncology.org for any questions.

 

Translational Science Workshop
The NRG Oncology Translational Science Workshop will feature highlights on emerging radiomics approaches to human cancers, artificial intelligence approaches to glioblastoma, and updates on the new tumor banking organization. Click here for the session flyer

 

Digital Health Workshop

The NRG Oncology Digital Health Workshop will include presentations from John Gannon of Blue Spark Technologies, Dr. Julian Hong of the University of California, San Francisco, and Dr. Sanjay Aneja of the Yale School of Medicine. Click here for the session flyer

 

Social Media Workshop 1-on-1's at #NRG19

Are you ready to get started on Twitter?  Let our social media experts show you how simple it is to set up a new account or make your existing account more engaging. At #NRG19, we have scheduled two Social Media 1-on-1 Workshops during which our Twitter experts will be on hand to show you the how-to's of Twitter. If you are interested in learning more about tweeting, retweeting, hashtags, following, and more, stop by during one of the following sessions and bring your smartphone and/or laptop. No previous social media experience required! Friday, July 19, 12:30-1pm and Saturday, July 20, 10-11am. Meet the experts here


PROTOCOL ACTIVITY

HEAD AND NECK

NRG-HN005: Activation Date: July 10, 2019 (posted on CTSU)

AMENDMENTS

BRAIN

CCTG CE.7: Amendment 1 version date April 11, 2019. This study was amended to add hippocampal sparing as part of whole brain radiotherapy, along with associated changes to the RTQA process and the addition of an NRG Oncology Study Chair. NRG Oncology sites are encouraged to enroll to the trial and credit NRG. For further details, please refer to the CE7 Letter to Investigators dated May 27, 2019, on the CTSU website (Supplemental Documents > Amendment 1 Memo).


GASTROINTESTINAL

RTOG 1112: Reopened to Accrual and Amendment 7 version date: June 28, 2019. Pending IRB approval of amendment 7, the study is open to new enrollment (posted on CTSU).

LUNG

NRG-LU003: Action Letter for Brigatinib and Protocol Amendments 1-2 (broadcast July 11, 2019).  Documents posted on CTSU website.


OTHER PROTOCOL NOTICES

1. CANCER PREVENTION AND CONTROL
NRG-CC004: ( NCORP and limited sites) A newsletter and slides from the June 19 webinar are posted on the study-specific page of the NRG website.


2. BREAST

NRG-BR004: Reminder – updated Pathology Instructions; version date June 27, 2019 (posted on  CTSU)

NRG-BR004: Memo regarding Tumor Submission has been posted on CTSU.

 

NSABP B-55/BIG 6-13: OlympiA Progress Report (posted to NRG Oncology website)


3. GYNECOLOGIC

NRG-GY009: Block Submission Reminder memo (posted on  CTSU)

Form TR for Biospecimens Shipped to NRG Biospecimen Bank-Columbus Read more

 

Biospecimen Bank-Columbus and SDMC Undergoing Refurbishment Read more


4. LUNG

NRG-LU003: Overview slides are available on the CTSU website.


5. VTOC TRAINING

The  VTOC Webinar Training Series schedule and registration is available for NRG Oncology Research Associates working on RTOG 0924, RTOG 0920, NRG-HN001, NRG-HN002, NRG-CC003, and NRG-CC004. The VisionTree staff will be at the round table session during the NRG Oncology Semiannual Meeting on July 18. Please stop by to learn more about VTOC.

DRUG SAFETY UPDATES

Safety updates have been issued for the following studies:

 

DRUG NAME

PROTOCOL

WEBSITE FOR SAFETY REPORTS

Atezolizumab

NRG-LU005
NRG-GY009

NRG-GY017
NRG-BR004

NRG-GI004

CTSU
CTSU
NRG
CTSU
CTSU

Ipilimumab

NRG-BN002
NRG-GY003

NRG

NRG

Nivolumab

NRG-BN002

NRG-GY003

NRG

NRG

Olaparib

NSABP B-55

CTSU

 

 

REMINDER ABOUT PRIMARY AND SECONDARY ROLES

NRG Oncology Members are required to designate individuals to fill the NRG Oncology Primary and Secondary Roles. Primary Roles are: Check Addressee, Contact PI, LAPS PI, Lead RA, Co-Lead RA (is optional), Local Lead RA and Principal Investigator (A maximum of 3 and the contact PI is counted as 1). Secondary Roles are: Contract Contact and Fiscal Contact. These roles are used to communicate with respect to NRG Oncology studies and information. In order for a person to be assigned a Role, he/she must have an active CTEP ID and be listed on the site's NRG Oncology Roster for the specific institution. The Roster Update Management System (RUMS) allows authorized people at clinical sites to manage roster data using a web-based application. Authorized persons can use RUMS to manage person roles, to request the addition or withdrawal of persons to their associated clinical sites, and to request the addition or withdraw of child sites from their local network. NCORP authorized users should request rostering of NCORP sites, investigators, and research associates via NCORP-SYS. A person must be rostered before any roles can be requested in RUMS.  Please take a moment to review your roster using the RUMS system to ensure that all of your network personnel are up to date.  Contact roster@nrgoncology.org or 412-339-5292 for assistance.

NRG Oncology is pleased to report the scientific articles and abstracts that have appeared or have been presented during the previous week. This publications report includes links, when available, to the article, PubMed abstract, or association abstract.

JOURNAL ARTICLES

Rosenthal SA, Hu C, Sartor O, Feng FY, Sandler HM. Reply to J.B. Aragon-Ching. J Clin Oncol. 2019 Jul 1:JCO1901332. doi: 10.1200/JCO.19.01332. [Epub ahead of print] PubMed PMID: 31260645.https://www.ncbi.nlm.nih.gov/pubmed/31260645. Correspondence.   Read more


ACCEPTED MEETING ABSTRACTS

ASTRO (American Society for Radiation Oncology) Sep 15-18, 2019


Awan M, Gittleman H, Barnholtz-Sloan J, Machtay M, Nguyen-Tan PF, Rosenthal DI, Takiar V, Garden AS, Thorstad W, Wong S, Trotti A, Birrer MJ, Sigurdson ER, Shenouda G, Mishra MV, Bahig H, Harris J, Le Q, Yao M. A.  Nomogram for Outcomes After Chemoradiation for Non-HPV-Related Squamous Cell Carcinomas of the Head And Neck – A Pooled Analysis of RTOG 0129 and 0522. Poster.


Craig T, Xiao Y, Dawson LA. Insights from IGRT Credentialing for the NRG Oncology RTOG 1112 Liver Trial.  Abst 1090. Mini Oral presentation.


Gondi V, Pugh SL, Brown P, Wefel JS, Tome WA, Bruner D, Bovi JA, Robinson C, Khuntia D, Grosshans D, Konski A, Roberge D, Kundapur V, Devisetty K, Shah S, Usuki K, Anderson BM, Mehta MP, Kachnic L. Significant Preservation of Neurocognitive Function (NCF) and Patient-Reported Symptoms with Hippocampal Avoidance (HA) during Whole-Brain Radiotherapy (WBRT) for Brain Metastases: Final Results of NRG Oncology CC001. Abst 23.


Men K, Geng H, Biswas T, Liao Z, Xiao Y. Quality assurance of contouring for RTOG 1308 Clinical Trial based on automated segmentation with deep active learning. Oral presentation.


Ryu S, Deshmukh S, Timmerman RD, Movsas B, Gerszten P, Yin F, Dicker A, Shiao SL, Desai A, Mell LK, Iyengar P, Hitchcock YJ, Allen AM, Burton S, Brown D, Sharp HJ, Chesney JA, Siddiqui MS, Chen TH, Kachnic LA. Radiosurgery Compared To External Beam Radiotherapy for Localized Spine Metastasis: Phase III Results of NRG Oncology/RTOG 0631. Oral presentation.


Yeung A, Pugh S, Klopp A, Gil K, Wenzel L, Westin SN, Konski A, Thompson JS, Doncals DE, Cantuaria GH, D'Souza DP, Chang A, Kundapur V, Mohan DS, Haas ML, Kim YB, Ferguson CL, Kachnic LA, Bruner D. IMRT improves late toxicity compared to conventional RT: An update on NRG Oncology-RTOG 1203. Oral presentation.


PUBLICATIONS REMINDERS

Please note the following upcoming meeting and abstract submission deadline dates


Upcoming Meetings

American Association of Physicists in Medicine (AAPM); Jul 14-18, 2019; San Antonio, TX

American Society for Radiation Oncology (ASTRO); Sep 15-18, 2019 ; Chicago, IL


International Gynecologic Cancer Society (IGCS)
; Sep 19-20, 2019; Rio de Janeiro, Brazil


Society for Neuro -Oncology (SNO) Inaugural Conference on Brain Metastases
; Aug 16-17, 2019; New York City, NY


Upcoming Abstract Submission Deadlines

European Society for Medical Oncology (ESMO); Sep 27-Oct 1, 2019; Barcelona, Spain; LBA Aug 21, 2019 9:00pm CEST


San Antonio Breast Cancer Symposium (SABCS)
; Dec 10-14, 2019; San Antonio, TX; due to publications committee Jun 24, 2019; meeting submission deadline Jul 8, 2019

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