April 15, 2019
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NCI ComboMatch Study

NRG Oncology is soliciting concepts for the NCI ComboMatch study.  Read more


CLOSURES AND SUSPENSIONS

BREAST

NSABP B-55/BIG 6-13: Reminder! Accrual closure memo (posted on CTSU)

 

GASTROINTESTINAL

NRG-GI002: Time Sensitive! Pending temporary accrual suspension memo (posted on CTSU)

 

GYNECOLOGIC

NRG-GY016: Temporarily closed to accrual on April 10, 2019 (posted on CTSU)


OTHER PROTOCOL NOTICES

1. CANCER CARE DELIVERY RESEARCH

NRG-CC007CD: A Participant Brochure is available on CTSU (CIRB Documents > Amendment Reviews > Support Documents #1). 

 

2. DEVELOPMENTAL THERAPEUTICS

NRG-DT001: Reminder and Update

Cohort A (extremity/body wall) was temporarily closed to accrual on March 12, 2019, with 3 p53 wild-type patients enrolled at dose level 1. Cohort A is anticipated to be reopened around mid-May 2019 when all 3 patients have completed the DLT evaluation period.

 

Cohort B (abdomen/pelvis/retroperitoneum) is still open to accrual at dose level 1. There is 1 p53 wild-type patient currently enrolled in Cohort B. We encourage all investigators to continue to keep eligible patients in mind for Cohort B.

 

3. GYNECOLOGIC

OUTBACK/GOG-0274/RTOG 1174: REMINDER! - Please submit all outstanding data and respond to all queries as quickly as possible.  This is needed so an analysis of the primary end point can be performed.    

 

NRG-GY009: Block Submission Reminder memo (posted on  CTSU)

 

Form TR for Biospecimens Shipped to NRG Biospecimen Bank-Columbus Read more

 

Biospecimen Bank-Columbus & SDMC Undergoing Refurbishment Read more

4. VTOC TRAINING

The VTOC Webinar Training Series schedule and registration is available for NRG Oncology Research Associates working on RTOG 0924, RTOG 0920, NRG-HN001, NRG-HN002, NRG-CC003, and NRG-CC004. Space is limited so register now and reserve your seat. The next webinar training is scheduled for Wednesday, May 8.

 

DRUG SAFETY UPDATES

Safety updates have been issued for the following studies:

DRUG NAME

PROTOCOL

WEBSITE FOR SAFETY REPORTS

Atezolizumab

NRG-GY009

NRG-GY017

CTSU

NRG

Nivolumab

 

NRG-BN002

NRG-GY003

NRG

NRG

Reolysin

GOG-0186H

NRG

 

 

NCI ComboMatch Study

NRG Oncology is soliciting concepts for the NCI ComboMatch study. This trial will focus on rational combinations of agents supported by preclinical in vivo evidence.Submission Due Date: May 30, 2019.  Please note that IO combinations are NOT permitted for the ComboMatch study.  Read more

NRG Oncology is pleased to report the scientific articles and abstracts that have appeared or have been presented during the previous week. This publications report includes links, when available, to the article, PubMed abstract, or association abstract.


JOURNAL ARTICLES

Hallemeier CL, Zhang P, Pisansky TM, Hanks GE, McGowan DG, Roach M 3rd, Zeitzer KL, Firat SY, Husain SM, D'Souza DP, Souhami L, Parliament MB, Rosenthal  SA, Lukka HR, Rotman M, Horwitz EM, Miles EF, Paulus R, Sandler HM. Prostate-specific antigen after neoadjuvant androgen suppression in prostate cancer patients receiving short-term androgen suppression and external beam radiotherapy: pooled analysis of four NRG Oncology RTOG randomized clinical trials. Int J Radiat Oncol Biol Phys. 2019 Apr 5. pii: S0360-3016(19)30610-8. doi: 10.1016/j.ijrobp.2019.03.049. [Epub ahead of print] PubMed PMID: 30959123.   Read more


PUBLICATIONS REMINDERS

Please note the following upcoming meeting and abstract submission deadline dates

Upcoming Meetings

American Association for Thoracic Surgery (AATS); May 4-7, 2019; Toronto, ON

American College of Radiology (ACR); May 18-22, 2019 ; Washington DC

ESMO Breast Cancer Annual Congress; May 2-4, 2019; Berlin, Germany

European Society for Radiotherapy and Oncology (ESTRO); Apr 26-30, 2019; Milan, Italy

Society for Clinical Trials (SCT); May 19-22, 2019; New Orleans, LA


Upcoming Abstract Submission Deadlines

European Society of Gynaecolocial Oncology (ESGO) Biennial; Nov 2-5, 2019; Athens, Greece; due to publications committee Apr 19, 2019; meeting submission deadline May 3, 2019

European Society for Medical Oncology (ESMO); Sep 27-Oct 1, 2019; Barcelona, Spain; due to publications committee Apr 30, 2019; meeting submission deadline May 8, 2019 9 pm CEST (Central European Summer Time); LBA Aug 21, 2019 9:00 pm CEST

International Gynecologic Cancer Society (IGCS); Sep 19-20, 2019; Rio de Janeiro, Brazil; due to publications committee Apr 8, 2019; meeting submission deadline Apr18, 2019

NRG Oncology is proud to be an active participant of #CancerMoonShot.
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